The automobile logistics could be divided into supply logistics (automotive parts inbound logistics), production logistics, distribution logistics and returned logistics. As part of the automobile logistics, automotive parts inbound logistics is highly technical and characterized by a high level of complexity. It is also recognized as the key point of good operation of automotive logistics system. Based on the analysis of automotive parts inbound logistics, the paper describes the optimization direction of automotive parts inbound logistics. Then it focuses on application of operations research in automotive parts inbound logistics optimization, builds a mathematical model and applies greedy algorithms to solve it.