The response of turbulent enstrophy to a sudden implementation of spanwise wall oscillation (SWO) is studied in a turbulent channel flow via direct numerical simulation. In the beginning of the application of SWO, a significant correlation is formed between ω'y and ω'z. A transient growth of turbulent enstrophy occurs, which directly enhances turbulent dissipation and drifts the turbulent flow towards a new lower-drag condition. Afterwards, the terms related to the stretching of vorticity (ωx, ω'y, and ωz), the inclination of ω'y by ∂w/∂y, the turn of ωz by ∂v'/∂z, and the horizontal shear of ωz by ∂w'/∂x are suppressed due to the presence of SWO, leading to attenuation of the turbulent enstrophy.